SCHEMBL11080248

C=C(C)C(=O)OCCC[Si](O[Si](C)(C)CCCO)([Si]1(C)CCC(C)(C)O[Si]1(C)C)[Si]1(C)CCC(C)(C)O[Si]1(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11075269	0.93	TSHR (0.32)	TSHR
SCHEMBL11066314	0.90	TSHR (0.30)	TSHR
SCHEMBL11076162	0.90	TSHR (0.30)	TSHR
SCHEMBL9001670	0.80	TSHR (0.34)	TSHR
SCHEMBL7547584	0.75	TSHR (0.49)	TSHR
SCHEMBL10595376	0.75	THRB (0.31)	TSHR
SCHEMBL9576342	0.72	TSHR (0.45)	TSHR
SCHEMBL6346524	0.72	TSHR (0.45)	TSHR
SCHEMBL14749000	0.72	TSHR (0.45)	TSHR
SCHEMBL9714979	0.72	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4463149-A	UNSATURATED POLYSILOXANES	POLYMER TECHNOLOGY CORPORATION (US)	1984-07-31	—	—	US	claimed
US-4463149-A	UNSATURATED POLYSILOXANES	POLYMER TECHNOLOGY CORPORATION (US)	1984-07-31	—	—	US	disclosed