Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089517 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL11078045 | 0.85 | SLC6A2 (0.42) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL11079087 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL11079091 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL11086716 | 0.79 | SLC6A4 (0.40) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL11115661 | 0.78 | KDM1A (0.40) | MEN1KMT2ASLC6A2SLC6A4SLC22A1 | |
| SCHEMBL11088698 | 0.78 | KDM1A (0.38) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL11082812 | 0.76 | SLC6A4 (0.40) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL11090776 | 0.76 | KDM1A (0.42) | MEN1KMT2ASLC6A2SLC6A4SLC22A1 | |
| SCHEMBL11087953 | 0.75 | KMT2A (0.44) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448991-A | ANALGESICS | HOFFMANN-LA ROCHE INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4336268-A | Cyclohexene derivative analgesics | HOFFMANN-LA ROCHE INC. (US) | 1982-06-22 | — | — | US | disclosed |