Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319059 | 0.79 | CHRM2 (0.42) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL9407831 | 0.73 | CHRM3 (0.38) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407787 | 0.73 | DRD2 (0.36) | KDM1ASLC6A2CHRM2CHRM4CHRM5 | |
| SCHEMBL9407789 | 0.73 | DRD2 (0.36) | KDM1ASLC6A2CHRM2CHRM4CHRM5 | |
| SCHEMBL9407763 | 0.73 | MAPK1 (0.33) | KDM1ASLC6A2CHRM2CHRM4CHRM5 | |
| SCHEMBL9407767 | 0.73 | MAPK1 (0.33) | KDM1ASLC6A2CHRM2CHRM4CHRM5 | |
| SCHEMBL9407828 | 0.73 | CHRM3 (0.38) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407759 | 0.73 | MAPK1 (0.33) | KDM1ASLC6A2CHRM2CHRM4CHRM5 | |
| SCHEMBL9407832 | 0.73 | CHRM3 (0.38) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9407792 | 0.73 | DRD2 (0.36) | KDM1ASLC6A2CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442296-A | LARVICIDES | FMC CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |
| US-4408057-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-10-04 | — | — | US | disclosed |
| US-4368205-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |