Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909990 | 0.86 | PKM (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10909994 | 0.86 | PKM (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10909123 | 0.85 | PKM (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL10909127 | 0.85 | PKM (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL10910747 | 0.85 | PKM (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL10908609 | 0.82 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10908614 | 0.82 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11036809 | 0.70 | CYP2A13 (0.35) | PDE4D | |
| SCHEMBL11036807 | 0.70 | CYP2A13 (0.35) | PDE4D | |
| SCHEMBL11082314 | 0.70 | CYP2A13 (0.35) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447428-A | BRONCHODILATOR, ANTICOAGULANTS | GLAXO GROUP LIMITED (GB) | 1984-05-08 | — | — | US | disclosed |
| US-4409213-A | B-SIDE CHAIN ATTACHED THRU AMINO GROUP; BRONCHODILATORS, ANTICOAGUANT | GLAXO GROUP LIMITED (GB) | 1983-10-11 | — | — | US | disclosed |
| US-4265891-A | PROSTAGLANDINS, BRONCHODILATORS, PLATELET AGGREGATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 1981-05-05 | — | — | US | disclosed |