Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072603 | 0.91 | TDP1 (0.37) | TDP1HPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11078044 | 0.91 | EPHX2 (0.40) | TDP1HPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11075301 | 0.89 | LMNA (0.39) | LMNAALDH1A1SMN1; SMN2NPSR1RAB9A | |
| SCHEMBL11079262 | 0.85 | TDP1 (0.49) | TDP1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11079265 | 0.85 | TDP1 (0.49) | TDP1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11074228 | 0.83 | MEN1 (0.38) | ALDH1A1SMN1; SMN2RAB9ANPC1EPHX2 | |
| SCHEMBL11073529 | 0.82 | CARM1 (0.38) | LMNAALDH1A1NPSR1RAB9ANPC1 | |
| SCHEMBL11079072 | 0.82 | EPHX2 (0.40) | HPGDLMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11079539 | 0.81 | EPHX2 (0.39) | RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL11077930 | 0.81 | PPARD (0.36) | LMNARAB9ANPC1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |