SCHEMBL1108058

SCHEMBL1108058

CN(C)c1cc[n+](Cc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHKA P35790 14/20 1.00
ALDH1A1 P00352 4/20 0.80
HTT P42858 3/20 0.80
SMN1; SMN2 Q16637 3/20 0.80
LMNA P02545 2/20 0.80
MITF O75030 1/20 0.56
MAPT P10636 1/20 0.56
NR2F2 P24468 1/20 0.56
KDM4E B2RXH2 1/20 0.56
RAB9A P51151 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108048 0.89 CHKA (1.00) CHKAALDH1A1HTTSMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL580650 0.87 CHKA (0.96) CHKAALDH1A1HTTSMN1; SMN2LMNA
Fluoride Ion SCHEMBL126024 0.86 CHKA (0.93) CHKAALDH1A1HTTSMN1; SMN2LMNA
Fluoride Ion SCHEMBL126023 0.86 CHKA (0.93) CHKAALDH1A1HTTSMN1; SMN2LMNA
SCHEMBL1108037 0.83 CHKA (0.70) CHKAALDH1A1HTTSMN1; SMN2LMNA
SCHEMBL10062535 0.82 CHKA (0.96) CHKAALDH1A1HTTSMN1; SMN2LMNA
SCHEMBL14557472 0.81 CHKA (0.67) CHKAALDH1A1HTTSMN1; SMN2LMNA
SCHEMBL10062537 0.79 CHKA (1.00) CHKAALDH1A1HTTSMN1; SMN2LMNA
SCHEMBL13851327 0.79 CHKA (0.71) CHKAALDH1A1HTTSMN1; SMN2LMNA
Bromide SCHEMBL29616684 0.77 CHKA (1.00) CHKAALDH1A1HTTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240069257-A1 CHOLESTERIC LIQUID CRYSTAL LAYER, METHOD OF FORMING CHOLESTERIC LIQUID CRYSTAL LAYER, LAMINATE, LIGHT GUIDE ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2024-02-29 US disclosed
US-11828960-B2 Cholesteric liquid crystal layer, method of forming cholesteric liquid crystal layer, laminate, light guide element, and image display device FUJIFILM CORPORATION (JP) 2023-11-28 US disclosed
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7658864-B2 Liquid crystal composition, optical compensation film and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-09 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090009693-A1 Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
WO-2007037497-A9 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORP (JP) 2007-05-24 WO disclosed