Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 14/20 | 0.96 |
| ▸ | LMNA | P02545 | 3/20 | 0.96 |
| ▸ | HTT | P42858 | 3/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.96 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108048 | 0.98 | CHKA (1.00) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| Fluoride Ion SCHEMBL126023 | 0.94 | CHKA (0.93) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| Fluoride Ion SCHEMBL126024 | 0.94 | CHKA (0.93) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1108058 | 0.87 | CHKA (1.00) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19468736 | 0.83 | CHKA (0.68) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10062535 | 0.82 | CHKA (0.96) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14561873 | 0.81 | CHKA (0.71) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL8857345 | 0.79 | CHKA (0.71) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10062537 | 0.79 | CHKA (1.00) | CHKALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13851327 | 0.79 | CHKA (0.71) | CHKALMNAHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398358-B1 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-03-09 | — | — | EP | claimed |
| US-5041194-A | Using low melting mixture of aluminum halide and onium halide of nitrogen-containing compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-08-20 | — | — | US | claimed |
| EP-0398358-A2 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-11-22 | — | — | EP | claimed |
| WO-2023241958-A1 | A PROCESS FOR THE PHOTOLYTIC CHLORINATION OF HALOGENATED PYRIDINES WITH MOLECULAR CHLORINE | BASF SE (DE) | 2023-12-21 | — | — | WO | disclosed |
| EP-4293014-A1 | A PROCESS FOR THE PHOTOLYTIC CHLORINATION OF HALOGENATED PYRIDINES WITH MOLECULAR CHLORINE | BASF SE (DE) | 2023-12-20 | — | — | EP | disclosed |
| EP-1307499-B2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1307499-B1 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2006-10-25 | — | — | EP | disclosed |
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | disclosed |
| EP-1307499-A2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-05-07 | — | — | EP | disclosed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | disclosed |
| US-20020035234-A1 | Continuous preparation of polycarbonate | GENERAL ELECTRIC COMPANY | 2002-03-21 | — | — | US | disclosed |
| WO-2002008311-A2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001085825-A2 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2001-11-15 | — | — | WO | disclosed |
| EP-0404188-B1 | Non-aqueous electrolytic aluminum plating bath composition | NISSHIN STEEL CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0398358-B1 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5074973-A | Mixed melt containing aluminum halide, nitrogen-heterocyclic halides, additives, organic polymer | NISSHIN STEEL CO. LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5041194-A | Using low melting mixture of aluminum halide and onium halide of nitrogen-containing compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0404188-A1 | Non-aqueous electrolytic aluminum plating bath composition | NISSHIN STEEL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0398358-A2 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |