SCHEMBL1108076

SCHEMBL1108076

O=S(=O)(O)c1ccc(OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F)c(OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
USP2 O75604 1/20 0.48
TSHR P16473 1/20 0.48
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2C9 P11712 1/20 0.41
RECQL P46063 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.34
S1PR3 Q99500 1/20 0.33
HSD17B10 Q99714 1/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 3/20 0.31
HPGD P15428 1/20 0.31
XBP1 P17861 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108094 1.00 MAPT (0.48) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL1108102 1.00 MAPT (0.48) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL1108101 0.90 MAPT (0.41) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL1108111 0.90 MAPT (0.41) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL12925294 0.76 MRGPRX4 (0.40) TSHRCYP1A2CYP2C19CYP2C9RECQL
SCHEMBL24031074 0.75 TSHR (0.53) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL13612648 0.74 MAPT (0.44) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL14282534 0.74 MAPT (0.44) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL13612654 0.74 MAPT (0.44) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL2535201 0.73 LMNA (0.41) MAPTCYP2C19CYP2C9MRGPRX4S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7876403-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-7658864-B2 Liquid crystal composition, optical compensation film and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-09 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090180059-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-07-16 US disclosed
US-20090009693-A1 Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed