Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068271 | 0.93 | POLB (0.44) | HPGDALDH1A1POLBKDM4EMTNR1A | |
| SCHEMBL8092632 | 0.89 | BRD4 (0.47) | HPGDALDH1A1POLBKDM4EL3MBTL1 | |
| SCHEMBL10963748 | 0.80 | POLB (0.50) | HPGDALDH1A1POLBL3MBTL1USP2 | |
| SCHEMBL10964174 | 0.73 | PTGER4 (0.55) | POLBL3MBTL1 | |
| SCHEMBL2036620 | 0.72 | HPGD (0.73) | HPGDALDH1A1POLBGAA | |
| SCHEMBL8613427 | 0.71 | POLB (0.41) | HPGDALDH1A1POLBHTTL3MBTL1 | |
| SCHEMBL18665382 | 0.69 | TSHR (0.57) | HPGDALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL10591282 | 0.69 | POLB (0.52) | HPGDALDH1A1POLBL3MBTL1USP2 | |
| SCHEMBL1516136 | 0.68 | HPGD (0.71) | HPGDALDH1A1GAA | |
| SCHEMBL11075684 | 0.68 | KDM4E (0.49) | HPGDALDH1A1POLBKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |