Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080831 | 0.93 | HPGD (0.43) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL8092632 | 0.91 | BRD4 (0.47) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL10963748 | 0.81 | POLB (0.50) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL11075684 | 0.75 | KDM4E (0.49) | POLBALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL10964174 | 0.74 | PTGER4 (0.55) | POLBNCOR2L3MBTL1 | |
| SCHEMBL8613427 | 0.73 | POLB (0.41) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL1927410 | 0.71 | HPGD (0.66) | POLBALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL10591282 | 0.71 | POLB (0.52) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL9513587 | 0.69 | POLB (0.50) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL10272750 | 0.68 | ALDH1A1 (0.51) | POLBALDH1A1TSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |