Ethylene

Ethylene

SCHEMBL11080858

C=C.Cc1ccc(N)cc1.Cc1ccc2[nH]ccc2c1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.45
BRD4 O60885 1/20 0.44
AHR P35869 3/20 0.43
NR4A2 P43354 2/20 0.43
CYP2A6 P11509 2/20 0.43
F7 P08709 1/20 0.43
LTA4H P09960 1/20 0.43
F3 P13726 1/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
ALOX15 P16050 1/20 0.43
RAD51 Q06609 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL10464922 0.89 USP2 (0.43) ACHEAHRNR4A2CYP2A6F7
SCHEMBL30882 0.85 AHR (0.56) BRD4AHRNR4A2CYP2A6F7
SCHEMBL30138435 0.85 AHR (0.56) BRD4AHRNR4A2CYP2A6F7
Methane SCHEMBL27911673 0.83 AHR (0.54) BRD4AHRNR4A2CYP2A6F7
Cyanide SCHEMBL31107538 0.80 AHR (0.50) BRD4AHRNR4A2CYP2A6F7
SCHEMBL17291794 0.78 MEN1 (0.48) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL130519 0.77 AHR (0.56) AHRNR4A2CYP2A6F7LTA4H
SCHEMBL29560117 0.77 AHR (0.56) AHRNR4A2CYP2A6F7LTA4H
4-Chloroaniline SCHEMBL11084468 0.76 AHR (0.72) AHRNR4A2CYP2A6F7LTA4H
Iodide SCHEMBL7361153 0.75 AHR (0.54) AHRNR4A2CYP2A6F7LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436917-A REACTION OF ANILINE AND GLYCOL, CATALYST MITSUI TOATSU CHEMICALS, INC. (JP) 1984-03-13 US disclosed