Ethylene Glycol

Ethylene Glycol

SCHEMBL10464922

Cc1ccc(N)cc1.Cc1ccc2[nH]ccc2c1.OCCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
ALOX15 P16050 1/20 0.43
RAD51 Q06609 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
F2 P00734 1/20 0.41
MAOA P21397 2/20 0.41
MAOB P27338 1/20 0.41
ACHE P22303 1/20 0.41
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL11080858 0.89 ACHE (0.45) USP2GAAALOX15RAD51NPSR1
SCHEMBL30138435 0.81 AHR (0.56) USP2GAAALOX15RAD51NPSR1
SCHEMBL30882 0.81 AHR (0.56) USP2GAAALOX15RAD51NPSR1
Methane SCHEMBL27911673 0.79 AHR (0.54) USP2GAAALOX15RAD51NPSR1
Cyanide SCHEMBL31107538 0.76 AHR (0.50) USP2GAAALOX15RAD51NPSR1
Acetic Acid SCHEMBL9117852 0.75 PIN1 (0.50) USP2GAAALOX15RAD51NPSR1
SCHEMBL17291794 0.74 MEN1 (0.48) USP2GAAALOX15RAD51NPSR1
SCHEMBL130519 0.73 AHR (0.56) USP2GAAALOX15RAD51NPSR1
SCHEMBL29560117 0.73 AHR (0.56) USP2GAAALOX15RAD51NPSR1
SCHEMBL9119192 0.72 PIN1 (0.44) USP2GAAALOX15RAD51NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4937353-A Subjecting aniline and ethylene glycol to a gas phase catalytic reaction at a superatmospheric pressure MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-06-26 US disclosed