Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555569 | 0.85 | MAPT (0.44) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL27836710 | 0.83 | MAPT (0.42) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL8556527 | 0.83 | MAPT (0.42) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL1305452 | 0.81 | MAPT (0.55) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL1304857 | 0.79 | HDAC3 (0.44) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| SCHEMBL20702221 | 0.77 | CYP1A2 (0.42) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL5682426 | 0.74 | CYP2C19 (0.41) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL1348352 | 0.72 | MAPT (0.42) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| SCHEMBL8860523 | 0.71 | MAPT (0.50) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL1170985 | 0.71 | ALDH1A1 (0.42) | KMT2AMAPTCYP2C19HIF1AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442296-A | LARVICIDES | FMC CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |
| US-4408057-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-10-04 | — | — | US | disclosed |
| US-4368205-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |