Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085958 | 0.88 | CYP3A4 (0.54) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11031200 | 0.84 | MAPT (0.62) | MAPTPDE4BNPC1RAB9ATP53 | |
| Acetic Acid SCHEMBL11082070 | 0.84 | MAPT (0.59) | MAPTPDE4BNPC1RAB9ATP53 | |
| SCHEMBL11083167 | 0.83 | RXFP1 (0.53) | MAPTTP53SMN1; SMN2 | |
| SCHEMBL11082254 | 0.81 | MAPT (0.48) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11081196 | 0.80 | POLB (0.52) | NPC1HTTPOLBKMT2AMEN1 | |
| SCHEMBL4601893 | 0.80 | GRM4 (0.62) | MAPTPDE4BNPC1RAB9ATP53 | |
| SCHEMBL11077482 | 0.78 | CYP3A4 (0.53) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11590109 | 0.77 | KCNK3 (0.68) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL11075368 | 0.76 | MAPT (0.49) | MAPTNPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450167-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |