Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473361 | 0.87 | TDP1 (0.36) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL9859266 | 0.86 | CYP3A4 (0.32) | TDP1CYP3A4ALDH1A1HPGD | |
| SCHEMBL11535245 | 0.84 | TDP1 (0.34) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL11531900 | 0.81 | CYP3A4 (0.42) | TDP1MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL11532906 | 0.77 | TDP1 (0.36) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL11085804 | 0.75 | TDP1 (0.39) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL8088179 | 0.74 | CYP2D6 (0.37) | MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL1969003 | 0.73 | TDP1 (0.47) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL28559413 | 0.72 | TDP1 (0.42) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL11872777 | 0.71 | TDP1 (0.39) | TDP1MAPK1CYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465682-A | Combating pests with substituted 3,6-diphenyl-3,4-dihydro-2H-1,3,5-oxadiazine-2,4-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1984-08-14 | — | — | US | disclosed |
| US-4348394-A | Combating pests with substituted 3,6-diphenyl-3,4-dihydro-2H-1,3,5-oxadiazine-2,4-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4239762-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |