Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 17/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 17/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 17/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 7/20 | 0.40 |
| ▸ | CHRNA6 | Q15825 | 7/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 10/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708495 | 0.84 | PDE4B (0.35) | EPHX1 | |
| SCHEMBL13634298 | 0.83 | — | — | |
| SCHEMBL7329606 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL7329600 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL5386339 | 0.79 | GAA (0.46) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL20577099 | 0.78 | — | — | |
| SCHEMBL3867623 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL7290017 | 0.77 | CHRNB2 (0.32) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL3867618 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL3867628 | 0.77 | SMN1; SMN2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | claimed |
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | disclosed |