Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | SCN1A | P35498 | 2/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.56 |
| ▸ | HNF4A | P41235 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489710 | 0.90 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL5975125 | 0.89 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL5975366 | 0.89 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL7117091 | 0.89 | ALDH1A1 (0.63) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL5893357 | 0.88 | TSHR (0.73) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28029433 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL6399743 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27481795 | 0.86 | ALDH1A1 (0.90) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL6399746 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL21410539 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433145-A | HEAT AND LIGHT STABILIZERS FOR POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-21 | — | — | US | disclosed |