Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970486 | 0.84 | HRH3 (0.81) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL14970546 | 0.83 | HRH3 (0.89) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780187 | 0.80 | TDP1 (1.00) | HRH3HTR2AHTR7HTR6TDP1 | |
| Hydrochloric Acid SCHEMBL8780151 | 0.79 | HRH3 (0.97) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL491876 | 0.78 | HRH3 (0.97) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780201 | 0.78 | HRH3 (0.97) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL9330132 | 0.78 | CYP1A2 (0.77) | HTR2ATDP1MEN1KMT2ADRD3 | |
| SCHEMBL11538959 | 0.78 | HRH3 (0.56) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL11554137 | 0.78 | HRH3 (0.56) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL5856195 | 0.77 | HRH3 (0.94) | HRH3HTR2AHTR7HTR6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438116-A | Quinoxalinyloxy-amino-propanol compounds with blood pressure lowering and β-blocking properties, their use and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1984-03-20 | — | — | US | claimed |