Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.81 |
| ▸ | HTR2A | P28223 | 2/20 | 0.81 |
| ▸ | HTR7 | P34969 | 2/20 | 0.81 |
| ▸ | HTR6 | P50406 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | NOS3 | P29474 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD5 | P21918 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970546 | 0.92 | HRH3 (0.89) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780187 | 0.89 | TDP1 (1.00) | HRH3HTR2AHTR7HTR6TDP1 | |
| Hydrochloric Acid SCHEMBL8780151 | 0.88 | HRH3 (0.97) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780201 | 0.88 | HRH3 (0.97) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL491876 | 0.88 | HRH3 (0.97) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL5856195 | 0.87 | HRH3 (0.94) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL1374528 | 0.85 | TDP1 (0.63) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL1599356 | 0.85 | CNR1 (0.68) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL11082306 | 0.84 | HRH3 (0.67) | HRH3HTR2AHTR7HTR6TDP1 | |
| Oxalic Acid SCHEMBL8780050 | 0.84 | HRH3 (0.83) | HRH3HTR2AHTR7HTR6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |