Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 11/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 9/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157430 | 0.89 | SRD5A1 (0.76) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8157426 | 0.89 | SRD5A1 (0.76) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL790855 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL13970874 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL14355654 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL797723 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL13403338 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL790854 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL14295225 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL13950489 | 0.87 | SRD5A1 (0.73) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153648-B2 | Solid and crystalline dutasteride and processes for preparation thereof | GADOR S.A. (AR) | 2012-04-10 | — | — | US | disclosed |
| US-8153648-B2 | Solid and crystalline dutasteride and processes for preparation thereof | GADOR S.A. (AR) | 2012-04-10 | — | — | US | disclosed |
| US-20090203724-A1 | SOLID AND CRYSTALLINE DUTASTERIDE AND PROCESSES FOR PREPARATION THEREOF | GADOR S.A. (AR) | 2009-08-13 | — | — | US | disclosed |
| US-20090203724-A1 | SOLID AND CRYSTALLINE DUTASTERIDE AND PROCESSES FOR PREPARATION THEREOF | GADOR S.A. (AR) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203724-A1 | SOLID AND CRYSTALLINE DUTASTERIDE AND PROCESSES FOR PREPARATION THEREOF | AR, CYP21A2, CYP4A22 | SRD5A1 24/4885SRD5A2 20/4885LMNA 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.