Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083067 | 1.00 | POLB (0.51) | POLBTSHRTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL10439102 | 0.84 | POLB (0.64) | POLBTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL1796055 | 0.84 | POLB (0.64) | POLBTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL1796053 | 0.84 | POLB (0.64) | POLBTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11081721 | 0.83 | POLB (0.50) | POLBTSHRALDH1A1KMT2ACA1 | |
| SCHEMBL11081718 | 0.83 | POLB (0.50) | POLBTSHRALDH1A1KMT2ACA1 | |
| SCHEMBL11066332 | 0.82 | POLB (0.53) | POLBALDH1A1SMN1; SMN2SRD5A2KMT2A | |
| SCHEMBL2805466 | 0.82 | POLB (0.53) | POLBTSHRTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2805463 | 0.82 | POLB (0.53) | POLBTSHRTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL11076121 | 0.82 | POLB (0.53) | POLBALDH1A1SMN1; SMN2SRD5A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465630-A | Tetraazaannulene cobalt complex compounds and method for preparation therefor | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-08-14 | — | — | US | disclosed |
| EP-0073456-A1 | Tetraazaannulene cobalt complex compounds and method for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-03-09 | — | — | EP | disclosed |