SCHEMBL11076121

SCHEMBL11076121

Cc1ccc(/C(C=O)=C\N(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
ALDH1A1 P00352 6/20 0.42
LMNA P02545 5/20 0.42
HTT P42858 3/20 0.42
NPSR1 Q6W5P4 3/20 0.42
PKM P14618 2/20 0.42
ATM Q13315 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KMT2A Q03164 2/20 0.42
NLRP1 Q9C000 1/20 0.42
MEN1 O00255 1/20 0.42
NTSR1 P30989 1/20 0.42
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
GAA P10253 2/20 0.38
NQO2 P16083 2/20 0.38
MAPT P10636 2/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11066332 1.00 POLB (0.53) POLBALDH1A1LMNAHTTNPSR1
SCHEMBL11066346 1.00 POLB (0.53) POLBALDH1A1LMNAHTTNPSR1
SCHEMBL2805466 0.84 POLB (0.53) POLBALDH1A1LMNAHTTNPSR1
SCHEMBL2805463 0.84 POLB (0.53) POLBALDH1A1LMNAHTTNPSR1
SCHEMBL11083067 0.82 POLB (0.51) POLBALDH1A1SMN1; SMN2HPGDTDP1
SCHEMBL8303787 0.82 POLB (0.65) POLBALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL1239325 0.82 POLB (0.51) POLBALDH1A1LMNAHTTNPSR1
SCHEMBL11083064 0.82 POLB (0.51) POLBALDH1A1SMN1; SMN2HPGDTDP1
SCHEMBL11080951 0.82 POLB (0.65) POLBALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL11087637 0.82 POLB (0.51) POLBALDH1A1SMN1; SMN2HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4465630-A Tetraazaannulene cobalt complex compounds and method for preparation therefor ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-08-14 US disclosed
EP-0073456-A1 Tetraazaannulene cobalt complex compounds and method for preparation thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-03-09 EP disclosed