Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 7/20 | 0.84 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.84 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11085275 | 0.98 | ADRA1A (0.81) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| SCHEMBL7823280 | 0.91 | ADRA1A (1.00) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| SCHEMBL11087074 | 0.91 | ADRA1A (0.75) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7826281 | 0.90 | ADRA1A (0.98) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11089775 | 0.89 | ADRA1A (0.73) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11089794 | 0.89 | ADRA1A (0.73) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7837475 | 0.88 | ADRA1A (0.98) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| SCHEMBL10626194 | 0.87 | ADRA1A (0.78) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| SCHEMBL11084284 | 0.86 | ADRA1A (0.77) | ADRA1AADRA1BADRA2AADRA2BADRA2C | |
| SCHEMBL20630865 | 0.85 | ADRA1A (0.67) | ADRA1AADRA1BADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426382-A | HYPOTENSIVE AGENTS | SANKYO COMPANY LIMITED (JP) | 1984-01-17 | — | — | US | claimed |
| US-4426382-A | HYPOTENSIVE AGENTS | SANKYO COMPANY LIMITED (JP) | 1984-01-17 | — | — | US | disclosed |