SCHEMBL1108347

SCHEMBL1108347

Bc1ccccc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28782102 0.77 ALDH1A1 (0.68)
SCHEMBL21161871 0.75
SCHEMBL15514664 0.75
SCHEMBL4669536 0.73
SCHEMBL29351116 0.73
SCHEMBL5167521 0.73 CYP3A4 (1.00)
SCHEMBL6187 0.73
SCHEMBL29037263 0.72 CYP3A4 (0.77)
SCHEMBL24418727 0.71
SCHEMBL20333575 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024007520-A1 ORGANIC COMPOUND AND USE THEREOF 北京燕化集联光电技术有限公司 2024-01-11 WO disclosed
EP-4231064-A1 COMPOSITIONS AND USE THEREOF IN PHOTOELECTRIC FIELD Zhejiang Brilliant Optoelectronic Technology Co., Ltd. (CN) 2023-08-23 EP disclosed
US-20230167067-A1 PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES UNIV NORTH CAROLINA CHAPEL HILL (US) 2023-06-01 US disclosed
US-11584720-B2 Photoredox-catalyzed direct C-H functionalization of arenes THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-02-21 US disclosed
EP-3402799-B1 HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-05-04 EP disclosed
WO-2022079246-A1 NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2022-04-21 WO disclosed
WO-2021242955-A1 FUSED AZOLE HETEROCYCLES AS AHR ANTAGONISTS SENDA BIOSCIENCES, INC. (US) 2021-12-02 WO disclosed
US-10988488-B2 Process for the functionalization of sp2-H carbons using frustrated lewis pair catalysts UNIVERSITé LAVAL (CA) 2021-04-27 US disclosed
US-10759806-B2 Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors INFINITY PHARMACEUTICALS, INC. (US) 2020-09-01 US disclosed
WO-2020055113-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-03-19 WO disclosed
EP-1966158-B1 SUBSTITUTED CINNOLINE DERIVATIVES AS GABAA-RECEPTOR MODULATORS AND METHOD FOR THEIR SYNTHESIS ASTRAZENECA AB (SE) 2012-08-08 EP disclosed
US-8153758-B2 Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides AMBRX, INC. (US) 2012-04-10 US disclosed
WO-2012008435-A1 BIARYL AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF 大日本住友製薬株式会社 (JP) 2012-01-19 WO disclosed
WO-2011097260-A1 TRIS (ARYLBENZOXAZOLE) BENZENE AND TRIS (ARYLBENZOTHIAZOLE) BENZENE AS ORGANIC ELECTRON - TRANS PORT MATERIALS NITTO DENKO CORPORATION (JP) 2011-08-11 WO disclosed
US-20100273189-A1 NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS BECKMAN COULTER, INC. (US) 2010-10-28 US disclosed
US-7465795-B2 Compounds and uses thereof ASTRAZENECA AB (SE) 2008-12-16 US disclosed
US-7425556-B2 Compounds and uses thereof ASTRAZENECA AB (SE) 2008-09-16 US disclosed
EP-1694659-B1 THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS SCHERING CORP (US) 2008-08-27 EP disclosed
US-20080194459-A1 Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses AMBRX, INC. (US) 2008-08-14 US disclosed
US-20070142328-A1 Compounds and Uses Thereof ASTRAZENECA AB (SE) 2007-06-21 US disclosed