Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338267 | 0.88 | RAD52 (0.51) | GAAMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL14453287 | 0.78 | MAPT (0.52) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9499966 | 0.78 | GAA (0.47) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL16592515 | 0.76 | GAA (0.59) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2071884 | 0.76 | GAA (0.59) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6353701 | 0.76 | MAPT (0.59) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL24714329 | 0.75 | MAPT (0.57) | GAAMAPTSMN1; SMN2ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL9680698 | 0.75 | GAA (0.43) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL25091235 | 0.74 | MAPT (0.51) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9499986 | 0.74 | PTGER4 (0.49) | GAAMAPTSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |