SCHEMBL24714329

SCHEMBL24714329

COc1ccc(C)cc1NCC(N)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.57
▸ ALDH1A1 P00352 4/20 0.57
▸ HTT P42858 1/20 0.57
▸ GAA P10253 5/20 0.54
▸ TSHR P16473 3/20 0.54
▸ MAPK1 P28482 3/20 0.54
▸ TDP1 Q9NUW8 2/20 0.54
▸ L3MBTL1 Q9Y468 2/20 0.54
▸ LMNA P02545 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ MEN1 O00255 6/20 0.51
▸ KMT2A Q03164 6/20 0.51
▸ KDM4E B2RXH2 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ CRHBP P24387 1/20 0.50
▸ CRHR2 Q13324 1/20 0.50
▸ CASP3 P42574 1/20 0.49
▸ SENP7 Q9BQF6 1/20 0.49
▸ SENP6 Q9GZR1 1/20 0.49
▸ TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11338267 0.84 RAD52 (0.51) MAPTALDH1A1HTTGAATSHR
SCHEMBL18830675 0.82 CA12 (0.58) MAPTHTTGAATSHRMAPK1
SCHEMBL12895530 0.82 MAPT (0.61) MAPTALDH1A1HTTGAATSHR
SCHEMBL5534456 0.79 KMT2A (0.66) MAPTALDH1A1HTTGAATSHR
SCHEMBL11342106 0.79 MEN1 (0.68) MAPTALDH1A1HTTGAAMAPK1
SCHEMBL9391738 0.77 ALDH1A1 (0.40) MAPTALDH1A1HTTGAATSHR
SCHEMBL4387302 0.76 MAPT (0.63) MAPTALDH1A1HTTGAATSHR
SCHEMBL28858859 0.76 KMT2A (0.58) MAPTALDH1A1HTTGAATSHR
SCHEMBL11822323 0.76 MAPT (0.58) MAPTALDH1A1HTTGAATSHR
SCHEMBL6836535 0.76 CXCR2 (0.46) MAPTALDH1A1GAAMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240206469-A1 PHOSPHORUS USE EFFICIENCY ENHANCERS AS PLANT GROWTH PROMOTORS EUROCHEM ANTWERPEN (BE) 2024-06-27 — — US disclosed
US-20240206469-A1 PHOSPHORUS USE EFFICIENCY ENHANCERS AS PLANT GROWTH PROMOTORS EUROCHEM ANTWERPEN (BE) 2024-06-27 — — US disclosed
EP-4066640-A1 PHOSPHORUS USE EFFICIENCY ENHANCERS AS PLANT GROWTH PROMOTORS EuroChem Antwerpen (BE) 2022-10-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240206469-A1 PHOSPHORUS USE EFFICIENCY ENHANCERS AS PLANT GROWTH PROMOTORS P4HA1, MYB, HAO2 MAPT 4829/4885ALDH1A1 2718/4885HTT 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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