Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064330 | 0.95 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1NPSR1MAPTPTGER4 | |
| SCHEMBL11066385 | 0.95 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1NPSR1KDM4EMAPT | |
| SCHEMBL11068054 | 0.94 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1NPSR1KDM4EMAPT | |
| SCHEMBL11062542 | 0.94 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTPTGER4LMNA | |
| SCHEMBL11062208 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL11062617 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPSR1KDM4EMAPT | |
| SCHEMBL11068376 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1NPSR1KDM4EMAPT | |
| SCHEMBL11068175 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTPTGER4PKM | |
| SCHEMBL11072094 | 0.87 | PLA2G2A (0.37) | SMN1; SMN2 | |
| SCHEMBL11066294 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4EMAPTPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431819-A | PRESSURE AND HEAT SENSITIVE ELEMENTS; CARBONLESS COPYING; HECTOGRAPHY; XERORAPHY | STERLING DRUG INC. (US) | 1984-02-14 | — | — | US | claimed |