SCHEMBL1108408

SCHEMBL1108408

O=S(=O)(O)c1cccc(N(CC(O)COc2ccccc2)CC(O)Oc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
HIF1A Q16665 2/20 0.39
ABCB1 P08183 3/20 0.38
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 1/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CETP P11597 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108386 0.93 HIF1A (0.44) GAAHIF1AABCB1POLBL3MBTL1
SCHEMBL1108418 0.89 POLB (0.44) GAAHIF1AABCB1POLBL3MBTL1
SCHEMBL21792721 0.75 POLB (0.54) GAAHIF1AABCB1POLBL3MBTL1
SCHEMBL1108384 0.74 ALDH1A1 (0.41) ALDH1A1KMT2ATSHR
SCHEMBL12130988 0.73 KAT6A (0.39) GAAL3MBTL1ALDH1A1PKMKMT2A
SCHEMBL1108390 0.73 ALDH1A1 (0.37) GAAPOLBL3MBTL1ALDH1A1KDM4E
SCHEMBL1108385 0.72 CETP (0.42) L3MBTL1ALDH1A1KMT2ACETPTSHR
SCHEMBL13296458 0.72 HIF1A (0.44) HIF1AABCB1POLBL3MBTL1ALDH1A1
SCHEMBL1108391 0.70 GAA (0.46) GAAHIF1AABCB1POLBL3MBTL1
SCHEMBL14545171 0.69 MEN1 (0.54) ABCB1ALDH1A1KMT2AADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153283-B2 Magnetic recording medium, method of modifying surface of magnetic powder and magnetic coating material FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed