Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084141 | 1.00 | HRH3 (0.39) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL9798359 | 0.96 | HRH3 (0.41) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL9349666 | 0.96 | GRIA1 (0.39) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL9511984 | 0.96 | GRIA1 (0.39) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL9349673 | 0.96 | GRIA1 (0.39) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL10779619 | 0.96 | GRIA1 (0.39) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL9798346 | 0.96 | HRH3 (0.41) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL2352622 | 0.92 | GRIA1 (0.41) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL7751867 | 0.92 | GRIA1 (0.41) | HRH3KCNH2HRH2HRH1GRIA1 | |
| SCHEMBL2847079 | 0.91 | HRH3 (0.41) | HRH3KCNH2HRH2HRH1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439340-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1984-03-27 | — | — | US | disclosed |