Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771477 | 0.83 | AOC3 (0.54) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL28100250 | 0.83 | AOC3 (0.54) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL10776229 | 0.83 | AOC3 (0.54) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL10776215 | 0.83 | AOC3 (0.54) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL22413029 | 0.81 | ALOX5 (0.49) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL27586556 | 0.79 | AOC3 (0.57) | ALOX5PTGS2AOC3ELANE | |
| SCHEMBL11808022 | 0.78 | ALOX5 (0.53) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL28100184 | 0.78 | ALOX5 (0.45) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL28834539 | 0.78 | ALOX5 (0.45) | ALOX5PTGS2PPARAHTR2AAOC3 | |
| SCHEMBL24089314 | 0.76 | ALOX5 (0.43) | ALOX5PTGS2PPARAAOC3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487934-A | Method of preparing poly-substituted acylbenzenes | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1984-12-11 | — | — | US | disclosed |
| EP-0041682-B1 | A METHOD OF PREPARING POLY-SUBSTITUTED ACYLBENZENES | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-09-21 | — | — | EP | disclosed |
| EP-0041682-A1 | A method of preparing poly-substituted acylbenzenes | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1981-12-16 | — | — | EP | disclosed |
| US-4304941-A | Method of preparing poly-substituted acylbenzenes | HOECHST ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-12-08 | — | — | US | disclosed |