Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033195 | 0.93 | CYP3A4 (0.39) | TSHRTP53GAASMN1; SMN2RECQL | |
| SCHEMBL8814949 | 0.85 | TSHR (0.40) | TSHRTP53GAASMN1; SMN2RECQL | |
| SCHEMBL27746515 | 0.77 | GAA (0.50) | GAAKDM4EMEN1LMNAMAPT | |
| SCHEMBL22468826 | 0.73 | TSHR (0.36) | TSHRTP53GAASMN1; SMN2RECQL | |
| SCHEMBL2721962 | 0.73 | TSHR (0.36) | TSHRTP53GAASMN1; SMN2RECQL | |
| SCHEMBL29529763 | 0.73 | TSHR (0.36) | TSHRTP53GAASMN1; SMN2RECQL | |
| SCHEMBL1415539 | 0.73 | GRM8 (0.39) | TSHRKDM4EMEN1MAPTKMT2A | |
| SCHEMBL1058344 | 0.72 | TSHR (0.35) | TSHRTP53GAASMN1; SMN2RECQL | |
| SCHEMBL1019140 | 0.72 | TSHR (0.38) | TSHRTP53GAASMN1; SMN2RECQL | |
| SCHEMBL6328278 | 0.72 | ALDH1A1 (0.36) | TSHRTP53GAASMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474708-A | Process for the production of 1,4-bis-(dicyano-methylene)-cyclohexane | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |