Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 1.00 |
| ▸ | CYP11B2 | P19099 | 7/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672961 | 0.85 | CYP11B1 (0.74) | CYP11B1CYP11B2CYP19A1KMT2AKDM4E | |
| SCHEMBL15722807 | 0.80 | CYP11B1 (0.88) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL395505 | 0.80 | CYP11B1 (0.96) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL13105237 | 0.80 | CYP11B1 (0.72) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL15872000 | 0.79 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL28975968 | 0.79 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL23045637 | 0.78 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1KMT2AMEN1 | |
| SCHEMBL5489431 | 0.76 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL11245838 | 0.76 | CYP11B1 (0.60) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL16257971 | 0.74 | CYP11B1 (0.82) | CYP11B1CYP11B2CYP19A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850345-A | Quinoline functional nitrogen heterocyclic carbene ruthenium complex with multiple anti-cancer activities and preparation method thereof | 浙江树人学院 | 2023-03-28 | — | — | CN | claimed |
| US-4405634-A | Imidazole derivatives for treating myocardial infarction | BURROUGHS WELLCOME CO. (US) | 1983-09-20 | — | — | US | claimed |
| US-4396771-A | THROMBOEMBOLIC DISORDERS, SHOCK | BURROUGHS WELLCOME CO. (US) | 1983-08-02 | — | — | US | claimed |
| US-4357340-A | Imidazole derivatives and angina pectoris | BURROUGHS WELLCOME CO. (US) | 1982-11-02 | — | — | US | claimed |
| CN-115850345-A | Quinoline functional nitrogen heterocyclic carbene ruthenium complex with multiple anti-cancer activities and preparation method thereof | 浙江树人学院 | 2023-03-28 | — | — | CN | disclosed |
| CN-106478734-B | A kind of N-heterocyclic carbine ruthenium compound and its preparation method and application of the pyrazoles function dough with active anticancer | 浙江大学 | 2018-10-30 | — | — | CN | disclosed |
| CN-106478734-A | A kind of have N-heterocyclic carbine ruthenium compound of pyrazoles sense dough of active anticancer and its preparation method and application | 浙江大学 | 2017-03-08 | — | — | CN | disclosed |
| US-4431815-A | CARDIOTONIC AND ANTISHOCK AGENTS; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4425354-A | CARDIOVASCULAR DISORDERS | BURROUGHS WELLCOME CO. (US) | 1984-01-10 | — | — | US | disclosed |
| EP-0003732-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-10-19 | — | — | EP | disclosed |
| US-4405634-A | Imidazole derivatives for treating myocardial infarction | BURROUGHS WELLCOME CO. (US) | 1983-09-20 | — | — | US | disclosed |
| US-4396771-A | THROMBOEMBOLIC DISORDERS, SHOCK | BURROUGHS WELLCOME CO. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4357340-A | Imidazole derivatives and angina pectoris | BURROUGHS WELLCOME CO. (US) | 1982-11-02 | — | — | US | disclosed |
| EP-0003732-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-09-05 | — | — | EP | disclosed |