SCHEMBL5489431

SCHEMBL5489431

Cc1ccc(C)c(Cn2ccnc2)c1C

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 14/20 0.68
CYP11B2 P19099 12/20 0.68
CYP19A1 P11511 6/20 0.54
TBXAS1 P24557 2/20 0.49
CYP1A2 P05177 1/20 0.49
POLB P06746 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
MAPT P10636 1/20 0.49
QPCT Q16769 1/20 0.49
CYP4Z1 Q86W10 1/20 0.49
QPCTL Q9NXS2 1/20 0.49
CYP2A6 P11509 1/20 0.47
CYP2B6 P20813 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16672961 0.84 CYP11B1 (0.74) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL395505 0.83 CYP11B1 (0.96) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL15722807 0.83 CYP11B1 (0.88) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL28975968 0.81 CYP11B1 (1.00) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL13105237 0.78 CYP11B1 (0.72) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL11010710 0.78 POLB (0.60) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL23045637 0.77 CYP11B1 (0.64) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL16257971 0.76 CYP11B1 (0.82) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL10030556 0.76 CYP11B1 (0.82) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2
SCHEMBL11084608 0.76 CYP11B1 (1.00) CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157078-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-01-02 US claimed
US-20040170661-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2004-09-02 US claimed
US-6716421-B2 BAIT MATRICES AND BAIT STATIONS FOR ELIMINATING TERMITE COLONIES AND UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2004-04-06 US claimed
US-20030124164-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2003-07-03 US claimed
US-20030124166-A1 Termiticidal bait matrix can be used in a bait station installed in the ground. FLORIDA RESEARCH FOUNDATION, INC., THE UNIVERSITY OF 2003-07-03 US claimed
US-20030017187-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2003-01-23 US claimed
US-20020172658-A1 Devices and methods for eliminating termite colonies FLORIDA RESEARCH FOUNDATION, INC., THE UNIVERSITY OF 2002-11-21 US claimed
WO-2002069704-A2 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2002-09-12 WO claimed
US-7157078-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-01-02 US disclosed
US-6969512-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2005-11-29 US disclosed
US-6964124-B2 Devices and methods for eliminating termite colonies UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2005-11-15 US disclosed
US-20040170661-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2004-09-02 US disclosed
WO-2004032625-A2 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2004-04-22 WO disclosed
US-6716421-B2 BAIT MATRICES AND BAIT STATIONS FOR ELIMINATING TERMITE COLONIES AND UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2004-04-06 US disclosed
WO-2003105580-A1 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2003-12-24 WO disclosed
WO-2003106395-A1 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2003-12-24 WO disclosed
US-20030124164-A1 Devices and methods for eliminating termite colonies THE PROCTER & GAMBLE COMPANY 2003-07-03 US disclosed
US-20020172658-A1 Devices and methods for eliminating termite colonies FLORIDA RESEARCH FOUNDATION, INC., THE UNIVERSITY OF 2002-11-21 US disclosed
WO-2002069704-A2 DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030124166-A1 Termiticidal bait matrix can be used in a bait station installed in the ground. CA3, ADAMTS12, MMP7 CYP11B1 961/4885CYP11B2 1083/4885CYP19A1 4021/4885
US-20040170661-A1 Devices and methods for eliminating termite colonies CA3, MLN, TRHDE CYP11B1 914/4885CYP11B2 1062/4885CYP19A1 4210/4885
US-20030124164-A1 Devices and methods for eliminating termite colonies CA3, MLN, TRHDE CYP11B1 914/4885CYP11B2 1062/4885CYP19A1 4210/4885
US-20020172658-A1 Devices and methods for eliminating termite colonies CA3, MLN, TRHDE CYP11B1 914/4885CYP11B2 1062/4885CYP19A1 4210/4885
US-20030017187-A1 Devices and methods for eliminating termite colonies CA3, PHB1, COX6C CYP11B1 786/4885CYP11B2 1892/4885CYP19A1 3819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.