Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154652 | 0.91 | GAA (0.56) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL11514295 | 0.86 | GAA (0.50) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL1805339 | 0.86 | NPC1 (0.56) | GAANPC1TAAR1ALDH1A1MAPT | |
| Chloroneb SCHEMBL22739 | 0.84 | GAA (0.64) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL10798636 | 0.84 | CYP3A4 (0.41) | ALDH1A1MAPTKDM4EPOLBTSHR | |
| SCHEMBL6998497 | 0.82 | KMT2A (0.44) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL30487990 | 0.79 | GAA (0.65) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL3757554 | 0.79 | NPC1 (0.65) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL27952777 | 0.79 | GAA (0.65) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL16609990 | 0.76 | GAA (0.68) | GAANPC1TAAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455424-A | PIGMENTS AND DISPERSE DYES | SANDOZ LTD. (CH) | 1984-06-19 | — | — | US | claimed |
| US-4455424-A | PIGMENTS AND DISPERSE DYES | SANDOZ LTD. (CH) | 1984-06-19 | — | — | US | disclosed |
| US-4033963-A | Naphthoquinone derivatives | SANDOZ LTD. (CH) | 1977-07-05 | — | — | US | disclosed |
| US-3931163-A | PIGMENTS, DISPERSE DYES | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-01-06 | — | — | US | disclosed |