Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514295 | 0.91 | GAA (0.50) | NPC1GAATAAR1HSP90AA1ALDH1A1 | |
| SCHEMBL11084654 | 0.86 | GAA (0.50) | NPC1GAATAAR1HSP90AA1ALDH1A1 | |
| SCHEMBL16609990 | 0.82 | GAA (0.68) | NPC1GAATAAR1HSP90AA1ALDH1A1 | |
| SCHEMBL6154652 | 0.81 | GAA (0.56) | NPC1GAATAAR1HSP90AA1ALDH1A1 | |
| SCHEMBL9793506 | 0.80 | GAA (0.67) | NPC1GAATAAR1ALDH1A1MAPT | |
| SCHEMBL3757554 | 0.79 | NPC1 (0.65) | NPC1GAATAAR1HSP90AA1ALDH1A1 | |
| Chloroneb SCHEMBL22739 | 0.79 | GAA (0.64) | NPC1GAATAAR1HSP90AA1ALDH1A1 | |
| SCHEMBL1808576 | 0.74 | KDM4E (0.50) | NPC1GAAALDH1A1MAPTPKM | |
| SCHEMBL11416083 | 0.74 | ALDH1A1 (0.46) | GAAALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL30487990 | 0.74 | GAA (0.65) | NPC1GAATAAR1HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310623-A | THIO-PYRAZOLINE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1982-01-12 | — | — | US | claimed |
| US-4264723-A | CONTAINING PYRAZOLONE COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | claimed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-0854383-B1 | Silver halide color photographic light-sensitive material | KONISHIROKU PHOTO IND (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040176602-A1 | 3-Cyanoquinolines,3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors | WYETH | 2004-09-09 | — | — | US | disclosed |
| EP-0763774-B1 | Process for preparation of 2-equivalent 4-arylthio-5-pyrazolone magenta couplers | TULALIP CONSULTORIA COM SOCIED (PT) | 2003-04-02 | — | — | EP | disclosed |
| US-6156489-A | Silver halide photosensitive material | KONICA CORPORATION (JP) | 2000-12-05 | — | — | US | disclosed |
| US-6063555-A | PROVIDES SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL WHICH IS EXCELLENT IN SCENE DEPICTION ABILITY | KONICA CORPORATION (JP) | 2000-05-16 | — | — | US | disclosed |
| US-6027868-A | ORANGE COLORED BLACK AND WHITE PHOTOGRAPHIC NEGATIVE FILM | KONICA CORPORATION (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0651289-B1 | Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging | EASTMAN KODAK CO (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0232101-B1 | Light-sensitive silver halide color photographic material | KONISHIROKU PHOTO IND (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-4992357-A | Stability, adhesion resistant | KONICA CORPORATION (JP) | 1991-02-12 | — | — | US | disclosed |
| US-4914013-A | MAGENTA COUPLER HAVING SPECIFIC BALLAST GROUP | KONICA CORPORATION (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0350022-A2 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1990-01-10 | — | — | EP | disclosed |
| EP-0232101-A2 | Light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-08-12 | — | — | EP | disclosed |
| US-4587210-A | COLORFASTNESS; DISCOLORATION INHIBITION; MAGENTA COUPLERS; WHITE BACKGROUND | FUJI PHOTO FILM CO., LTD. (JP) | 1986-05-06 | — | — | US | disclosed |
| US-4310623-A | THIO-PYRAZOLINE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |
| US-4293691-A | Method for preparing magenta couplers having thioether groups | FUJI PHOTO FILM CO., LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| US-4264723-A | CONTAINING PYRAZOLONE COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176602-A1 | 3-Cyanoquinolines,3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors | PKD1, PKD2, CSNK1A1 | NPC1 653/4885GAA 3231/4885TAAR1 1532/4885 |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | IK, RB1, COL1A1 | NPC1 1531/4885GAA 2451/4885TAAR1 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.