Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067556 | 0.93 | ACE (0.47) | ACE | |
| SCHEMBL11070147 | 0.90 | ACE (0.66) | ACE | |
| SCHEMBL11067085 | 0.87 | ACE (0.63) | ACE | |
| SCHEMBL11077818 | 0.83 | ACE (0.55) | ACE | |
| SCHEMBL11070879 | 0.79 | ACE (0.69) | ACE | |
| Pentopril SCHEMBL109520 | 0.78 | ACE (0.67) | ACE | |
| Pentopril SCHEMBL109521 | 0.78 | ACE (0.67) | ACE | |
| Pentopril SCHEMBL7266503 | 0.78 | ACE (0.67) | ACE | |
| Pentopril SCHEMBL1133661 | 0.78 | ACE (0.67) | ACE | |
| Pentopril SCHEMBL7266499 | 0.78 | ACE (0.67) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479963-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0105919-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. | CIBA GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| WO-1983003828-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-11-10 | — | — | WO | disclosed |
| US-4374847-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-02-22 | — | — | US | disclosed |