Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084713 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| SCHEMBL11078184 | 0.91 | PLCG1 (0.55) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| SCHEMBL11078185 | 0.91 | PLCG1 (0.55) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| SCHEMBL11079599 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| SCHEMBL11079601 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| SCHEMBL1649485 | 0.88 | ALDH1A1 (0.70) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| SCHEMBL155070 | 0.88 | ALDH1A1 (0.70) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| Hydrochloric Acid SCHEMBL4312447 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| SCHEMBL11078285 | 0.87 | CYP3A4 (0.45) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 | |
| Hydrochloric Acid SCHEMBL1649518 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTHSD17B10SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |