Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.70 |
| ▸ | HTR1E | P28566 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083565 | 0.99 | CHRM3 (0.71) | CHRM3HTR1ES1PR3MEN1LMNA | |
| SCHEMBL27933777 | 0.84 | CHRM3 (0.72) | CHRM3HTR1ES1PR3MEN1LMNA | |
| SCHEMBL20202492 | 0.82 | CHRM3 (1.00) | CHRM3HTR1ES1PR3MEN1LMNA | |
| SCHEMBL15127557 | 0.82 | CHRM3 (0.74) | CHRM3HTR1ES1PR3MEN1LMNA | |
| SCHEMBL26162986 | 0.82 | SLC6A3 (0.59) | CHRM3LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20202491 | 0.81 | CHRM3 (1.00) | CHRM3HTR1ES1PR3MEN1LMNA | |
| SCHEMBL20412694 | 0.81 | CHRM3 (0.53) | CHRM3SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4875919 | 0.80 | CHRM3 (0.67) | CHRM3SIGMAR1 | |
| SCHEMBL19157195 | 0.79 | CHRM3 (0.48) | CHRM3HTR1ES1PR3MEN1KMT2A | |
| SCHEMBL4390848 | 0.79 | CHRM3 (0.48) | CHRM3HTR1ES1PR3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426382-A | HYPOTENSIVE AGENTS | SANKYO COMPANY LIMITED (JP) | 1984-01-17 | — | — | US | disclosed |