Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887558 | 0.71 | TSHR (0.43) | TDP1TRPA1ALDH1A1NPC1RAB9A | |
| Formaldehyde SCHEMBL26618259 | 0.67 | TDP1 (0.48) | TDP1TP53MEN1KMT2AALDH1A1 | |
| Formaldehyde SCHEMBL11059012 | 0.67 | TRPA1 (0.56) | TDP1TP53TRPA1MEN1KMT2A | |
| Formaldehyde SCHEMBL11059008 | 0.67 | TP53 (0.85) | TDP1TP53TRPA1MEN1KMT2A | |
| SCHEMBL31498554 | 0.66 | TDP1 (0.52) | TDP1TP53TRPA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31547677 | 0.66 | TDP1 (0.52) | TDP1TP53TRPA1MEN1KMT2A | |
| SCHEMBL3043421 | 0.66 | TDP1 (0.52) | TDP1TP53TRPA1MEN1KMT2A | |
| SCHEMBL3884170 | 0.65 | TDP1 (0.44) | TDP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Ethylene SCHEMBL25437124 | 0.64 | TDP1 (0.50) | TDP1TP53TRPA1SMN1; SMN2ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL4451014 | 0.64 | TDP1 (0.57) | TDP1TP53TRPA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433152-A | ANTIINFLAMMATORY AGENT, ANTIALLERGEN OR ANTICOAGULANT | NIPPON CHEMIPHAR CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |