Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504149 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL268172 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL10503461 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL11639935 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL10504055 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL10502771 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL11639760 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL8895243 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL7161132 | 0.98 | CES2 (0.50) | CES2POLBGMNNTP53MAPT | |
| Methane SCHEMBL15251905 | 0.96 | CES2 (0.48) | CES2POLBGMNNTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |