Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079212 | 0.97 | MEN1 (0.33) | NOS1HSD11B1CYP2C19F2RL1HSD17B10 | |
| SCHEMBL11077874 | 0.96 | F2RL1 (0.34) | NOS1F2RL1 | |
| SCHEMBL11083007 | 0.84 | ALDH1A1 (0.34) | NOS3NOS1NOS2HSD11B1CYP2C19 | |
| SCHEMBL11087918 | 0.81 | MEN1 (0.34) | NOS1HSD11B1F2RL1HSD17B10 | |
| SCHEMBL10833645 | 0.81 | KDM1A (0.34) | NOS1F2RL1KDM1AHSD17B10 | |
| SCHEMBL5049599 | 0.80 | PTGDR2 (0.42) | CYP2C19ALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL11079166 | 0.79 | F2RL1 (0.35) | NOS1F2RL1 | |
| SCHEMBL3979460 | 0.76 | PTGDR2 (0.45) | F2RL1HSD17B10OPRL1 | |
| Hydrochloric Acid SCHEMBL5051903 | 0.75 | PTGDR2 (0.44) | F2RL1HSD17B10OPRL1 | |
| SCHEMBL5051928 | 0.75 | PTGDR2 (0.48) | F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460600-A | Adjacently substituted ketal derivatives of cycloalkane-amide analgesics | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |