Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268818 | 0.80 | NCF1 (0.48) | NCF1GNAI3GNAO1GNAI1KEAP1 | |
| SCHEMBL805205 | 0.80 | NCF1 (0.48) | NCF1GNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL2128921 | 0.78 | NCF1 (0.52) | NCF1GNAI3GNAO1GNAI1KEAP1 | |
| Hydrochloric Acid SCHEMBL6709111 | 0.78 | NCF1 (0.46) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL20312253 | 0.78 | NCF1 (0.46) | NCF1GNAI3GNAO1GNAI1KEAP1 | |
| SCHEMBL11077478 | 0.78 | NCF1 (0.46) | NCF1GNAI3GNAO1GNAI1KEAP1 | |
| SCHEMBL590656 | 0.78 | — | — | |
| SCHEMBL11666183 | 0.78 | SMN1; SMN2 (0.42) | HTTLMNA | |
| SCHEMBL18502834 | 0.77 | NCF1 (0.45) | NCF1GNAI3GNAO1GNAI1KEAP1 | |
| SCHEMBL13621150 | 0.77 | NCF1 (0.45) | NCF1GNAI3GNAO1GNAI1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424225-A | ANTIULCER AGENTS | DR. KARL THOMAE GMBH (DE) | 1984-01-03 | — | — | US | disclosed |
| EP-0086982-A1 | Substituted thienobenzodiazepinones, process for preparing them and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1983-08-31 | — | — | EP | disclosed |