Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085670 | 1.00 | LMNA (0.33) | LMNAMAPK1ATMKDM4EALDH1A1 | |
| SCHEMBL11084705 | 0.87 | KMT2A (0.34) | LMNAMAPK1ATMKDM4EALDH1A1 | |
| SCHEMBL11084711 | 0.87 | KMT2A (0.34) | LMNAMAPK1ATMKDM4EALDH1A1 | |
| SCHEMBL11085667 | 0.78 | LMNA (0.43) | LMNAMAPK1ATMKDM4EALDH1A1 | |
| SCHEMBL10478000 | 0.70 | TSHR (0.45) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11614962 | 0.70 | TSHR (0.45) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL10987770 | 0.66 | NR4A2 (0.35) | LMNAALDH1A1MAPTGAAHPGD | |
| SCHEMBL11084707 | 0.65 | LMNA (0.44) | LMNAMAPK1ATMKDM4EALDH1A1 | |
| SCHEMBL10987765 | 0.63 | HDAC3 (0.55) | — | |
| SCHEMBL28769166 | 0.63 | HIF1A (0.45) | LMNAATMKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482553-A | ANTIBIOTICS, BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0122156-A2 | Improvements in or relating to benzothienylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |