Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 17/20 | 0.47 |
| ▸ | CTSD | P07339 | 5/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.45 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086616 | 0.96 | BACE1 (0.46) | FOLH1BACE1CTSDBACE2 | |
| SCHEMBL11087895 | 0.94 | FOLH1 (0.56) | FOLH1BACE1CTSDBACE2 | |
| SCHEMBL30973969 | 0.93 | FOLH1 (0.57) | FOLH1BACE1CTSDBACE2 | |
| SCHEMBL29630631 | 0.92 | FOLH1 (0.54) | FOLH1BACE1CTSDBACE2NMT2 | |
| SCHEMBL30836809 | 0.92 | FOLH1 (0.54) | FOLH1BACE1CTSDBACE2NMT2 | |
| SCHEMBL30432069 | 0.92 | NMT1 (0.48) | FOLH1BACE1CTSDBACE2NMT2 | |
| SCHEMBL29715043 | 0.92 | FOLH1 (0.49) | FOLH1BACE1CTSDBACE2NMT2 | |
| SCHEMBL29391811 | 0.92 | FOLH1 (0.48) | FOLH1BACE1CTSDBACE2NMT2 | |
| SCHEMBL38659209 | 0.92 | NMT2 (0.45) | FOLH1BACE1CTSDBACE2NMT2 | |
| SCHEMBL31319511 | 0.91 | NMT2 (0.44) | BACE1CTSDNMT2NMT1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442031-A | INTERNAL FRAGMENTS OF THYMOSIN A1 | HOFFMANN-LA ROCHE INC. (US) | 1984-04-10 | — | — | US | disclosed |