NMT2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3470768	1.00	18/20
SCHEMBL3472005	1.00	18/20
SCHEMBL3473477	1.00	18/20
SCHEMBL3472011	0.83	18/20
SCHEMBL3471351	0.81	18/20
SCHEMBL3470345	0.81	18/20
SCHEMBL3472069	0.80	18/20
SCHEMBL3475814	0.77	18/20
SCHEMBL3476799	0.76	18/20
SCHEMBL3470753	0.72	18/20
SCHEMBL3472706	0.68	18/20
SCHEMBL3472004	0.63	18/20
SCHEMBL3472756	0.62	18/20
SCHEMBL3472759	0.58	18/20
SCHEMBL3473958	0.52	18/20
SCHEMBL3475905	0.79	17/20
SCHEMBL3472236	0.76	17/20
SCHEMBL3472573	0.75	17/20
SCHEMBL3476012	0.74	17/20
SCHEMBL3475864	0.70	17/20

Clinical trials — most relevant to NMT2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Effects of GLP-1 in Maturity-Onset Diabetes of The Young (MODY)	PHASE2/PHASE3	COMPLETED
NEO100 and High-Grade Meningioma	PHASE2	RECRUITING
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer	PHASE1/PHASE2	COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserine	EARLY_PHASE1	COMPLETED
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer	nan	UNKNOWN
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression	nan	COMPLETED
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside	nan	UNKNOWN
EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND)	nan	RECRUITING
NGLY1 Natural History	nan	COMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML)	nan	WITHDRAWN
Impact of Nicotinamide Riboside (NR) on Kidney Function in Patients Undergoing Cardiac Surgery	nan	NOT_YET_RECRUITING
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia	nan	UNKNOWN
Glycosylation in Patients With Galactosaemia	nan	COMPLETED
Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation	nan	COMPLETED
Identification and Characterization of Monogenic Diabetes	nan	COMPLETED
Genome Environment Microbiome and Metabolome in Autism Study	nan	COMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study)	nan	RECRUITING
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder	nan	RECRUITING
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Evaluation of Blood Protein O-GlcNAcylation Levels in Children	nan	RECRUITING
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam	nan	UNKNOWN
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
Cross-Sectional and Longitudinal Studies of Pre-Diabetes in the Pima Indians	nan	COMPLETED
Predisposition Genes in Monogenic Diabetes (DIAMONO)	nan	COMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan	nan	ENROLLING_BY_INVITATION
Chest Wall Deformities in Children - Epidemiological Data	nan	COMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NMT2 binder may also engage these)

Protein	Name	Similarity
Q9N181	—	1.000	Q9N181 →
P31717	—	1.000	P31717 →
Q5RAF3	—	1.000	Q5RAF3 →
A7YT82	—	1.000	A7YT82 →
NMT1	Glycylpeptide N-tetradecanoyltransferase 1	0.998	landscape →
Q8K1Q0	—	0.997	Q8K1Q0 →
O70311	—	0.997	O70311 →
O70310	—	0.995	O70310 →
O61613	—	0.994	O61613 →
Q9LTR9	—	0.993	Q9LTR9 →
NAT10	RNA cytidine acetyltransferase	0.985	landscape →
Q75EK2	—	0.984	Q75EK2 →
Q803R5	—	0.983	Q803R5 →
Q5R981	—	0.982	Q5R981 →
Q4KLT3	—	0.982	Q4KLT3 →
Q8N1G2	—	0.982	Q8N1G2 →
O74234	—	0.981	O74234 →
P46548	—	0.981	P46548 →
Q5U2Z5	—	0.980	Q5U2Z5 →
Q9DBC3	—	0.980	Q9DBC3 →
Q5ZJM3	—	0.980	Q5ZJM3 →
Q5XHF8	—	0.980	Q5XHF8 →
Q8TFN1	—	0.980	Q8TFN1 →
F4J8C6	—	0.979	F4J8C6 →
Q6GQ76	—	0.979	Q6GQ76 →
Q4KWH8	—	0.978	Q4KWH8 →
A7Z050	—	0.978	A7Z050 →
B3M1E1	—	0.978	B3M1E1 →
P97386	—	0.978	P97386 →
P14743	—	0.978	P14743 →