Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575567 | 0.90 | HPGD (0.55) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14383981 | 0.86 | CYP1A2 (0.57) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6901685 | 0.85 | MEN1 (0.49) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5376331 | 0.81 | MEN1 (0.65) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11709219 | 0.79 | MAPT (0.69) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8668348 | 0.79 | PDE7A (0.62) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10263365 | 0.79 | CYP3A4 (0.61) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8534010 | 0.78 | MAPT (0.62) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10607143 | 0.77 | MEN1 (0.62) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13220796 | 0.77 | HPGD (0.73) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023141-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-11 | — | — | EP | disclosed |
| US-4417917-A | BENZENE DISULFONIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-11-29 | — | — | US | disclosed |
| EP-0070041-A2 | Substituted benzenesulfonyl isocyanates and isothiocyanates and processes for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4310346-A | HERBICIDES AND PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |