Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.58 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30310237 | 0.85 | KMT2A (0.54) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL22587912 | 0.85 | MEN1 (0.54) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL6901685 | 0.84 | MEN1 (0.49) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL8996846 | 0.83 | SMN1; SMN2 (0.51) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL16029554 | 0.81 | MEN1 (0.52) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL11409450 | 0.81 | GSTP1 (0.54) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL28127 | 0.81 | PDE7A (0.55) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL29449334 | 0.81 | PDE7A (0.55) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL8563127 | 0.81 | MEN1 (0.59) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL27225074 | 0.81 | GSTP1 (0.54) | MEN1KMT2AGSTP1GSTM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646396-B | A kind of synthetic method of benzothiazole derivant | 上海应用技术学院 | 2018-09-14 | — | — | CN | claimed |
| CN-105324379-B | Benzimidazole derivatives as bromodomain inhibitors | 吉利德科学公司 | 2018-12-04 | — | — | CN | disclosed |
| CN-105646396-B | A kind of synthetic method of benzothiazole derivant | 上海应用技术学院 | 2018-09-14 | — | — | CN | disclosed |
| CN-105646396-A | Method for synthesizing benzothiazole derivatives | 上海应用技术学院 | 2016-06-08 | — | — | CN | disclosed |
| CN-102558018-B | Benzene sulphenamide derivative and the purposes in preparation antibacterials thereof | NANKAI UNIVERSITY (CN) | 2015-08-12 | — | — | CN | disclosed |
| CN-102775360-B | Triazole ring-containing asymmetric disulfide ether compounds, synthesis method and usage thereof | UNIV NANKAI | 2015-05-06 | — | — | CN | disclosed |
| CN-102775360-A | Triazole ring-containing asymmetric disulfide ether compounds, synthesis method and usage thereof | UNIV NANKAI | 2012-11-14 | — | — | CN | disclosed |
| CN-102558018-A | Benzene sulfamide derivative and applications thereof in producing antibacterial drugs | UNIV NANKAI | 2012-07-11 | — | — | CN | disclosed |
| US-7262318-B2 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| CN-1930121-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2007-03-14 | — | — | CN | disclosed |
| EP-1725524-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | Pfizer Products Incorporated (US) | 2006-11-29 | — | — | EP | disclosed |
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PFIZER INC | 2006-11-16 | — | — | US | disclosed |
| US-20050228015-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-10-13 | — | — | US | disclosed |
| WO-2005092845-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2005-10-06 | — | — | WO | disclosed |
| CN-1051305-C | Acylated aminophenyl urea compounds, their preparation and their use as herbicides and plant-growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2000-04-12 | — | — | CN | disclosed |
| US-5808164-A | Process for producing aromatic sulfides | PHILLIPE PETROLEUM COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5618981-A | Process for producing aromatic sulfides | PHILLIPS PETROLEUM COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228015-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | MEN1 4855/4885KMT2A 3530/4885GSTP1 874/4885 |
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PPARG, PPARA, PPARD | MEN1 4861/4885KMT2A 3601/4885GSTP1 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.