SCHEMBL11086985

SCHEMBL11086985

Cc1ccc(CS)cc1Cl

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.64
CYP3A4 P08684 2/20 0.46
ALDH1A1 P00352 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM1A O60341 1/20 0.41
KDM4E B2RXH2 1/20 0.39
CCR2 P41597 1/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
AGTR1 P30556 1/20 0.37
RAPGEF4 Q8WZA2 1/20 0.37
PNMT P11086 1/20 0.35
HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12107538 0.81 CYP3A4 (0.54) IDO1CYP3A4ALDH1A1NPSR1KDM1A
SCHEMBL1755262 0.79 MAPT (0.49) IDO1CYP3A4ALDH1A1NPSR1KDM1A
SCHEMBL4026046 0.79 CYP3A4 (0.48) IDO1CYP3A4ALDH1A1NPSR1KDM1A
SCHEMBL30031076 0.79 CYP3A4 (0.48) IDO1CYP3A4ALDH1A1NPSR1KDM1A
SCHEMBL232137 0.78 IDO1 (1.00) IDO1ALDH1A1PNMT
SCHEMBL5351507 0.78 IDO1 (0.52) IDO1CYP3A4ALDH1A1GAAMAPT
SCHEMBL3763570 0.77 CYP3A4 (0.46) IDO1CYP3A4ALDH1A1NPSR1KDM1A
SCHEMBL9073026 0.77 CYP3A4 (0.46) IDO1CYP3A4ALDH1A1NPSR1KDM1A
SCHEMBL8368071 0.77 CYP3A4 (0.46) IDO1CYP3A4ALDH1A1NPSR1KDM1A
SCHEMBL109221 0.77 CYP3A4 (0.52) CYP3A4ALDH1A1NPSR1KDM1APNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886723-A Synthesis method of 2-chloro-4-methylsulfonyl benzoic acid 辽宁龙田化工科技有限公司 2024-04-16 CN claimed
CN-117886723-A Synthesis method of 2-chloro-4-methylsulfonyl benzoic acid 辽宁龙田化工科技有限公司 2024-04-16 CN disclosed
US-4458079-A BACTERICIDES, FUNGICIDES BRISTOL-MYERS COMPANY (US) 1984-07-03 US disclosed