Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 1.00 |
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221828 | 0.89 | IDO1 (0.79) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL6011638 | 0.80 | IDO1 (0.67) | IDO1PNMTTAAR1SIGMAR1IGF1R | |
| Benzoic Acid SCHEMBL10930063 | 0.80 | IDO1 (0.63) | IDO1NPC1TSHR | |
| SCHEMBL29086995 | 0.78 | IDO1 (0.64) | IDO1PNMTTAAR1AHRTSHR | |
| SCHEMBL25693776 | 0.78 | IDO1 (0.64) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL11086985 | 0.78 | IDO1 (0.64) | IDO1PNMTALDH1A1 | |
| SCHEMBL3298586 | 0.78 | IDO1 (0.64) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL81462 | 0.77 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1IGF1R | |
| SCHEMBL29494831 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL17372921 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60149554-A | — | — | None | — | — | JP | disclosed |
| JP-60149555-A | — | — | None | — | — | JP | disclosed |
| JP-60155102-A | — | — | None | — | — | JP | disclosed |
| JP-60120856-A | — | — | None | — | — | JP | disclosed |
| JP-60115560-A | — | — | None | — | — | JP | disclosed |
| CN-114829362-A | Six-membered and five-membered aromatic ring derivative containing nitrogen heteroatom and used as SHP2 inhibitor | 成都倍特药业股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113621005-A | alpha-D-galactoside inhibitors of galectins | 格莱克特生物技术公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-107406478-B | alpha-D-galactoside inhibitors of galectins | 格莱克特生物技术公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-112608257-A | Synthesis method of sulfoxide compound | 新疆大学 | 2021-04-06 | — | — | CN | disclosed |
| US-10961231-B2 | NTCP inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-03-30 | — | — | US | disclosed |
| US-4268456-A | FROM A MERCAPTAN AND PHOSGENE, QUATERNARY AMMONIUM SALT CATALYST | PPG INDUSTRIES, INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4183924-A | 17α-Chloro-17β-hydrocarbonsulfinyl-1,4-androstadienes and the corresponding 17β-hydrocarbonsulfonyl derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1980-01-15 | — | — | US | disclosed |
| EP-0003863-A1 | Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-09-05 | — | — | EP | disclosed |
| EP-0002283-A1 | Substituted 1,3-dihydrospiro (benzo(c)thiophenes), process for their preparation and these compounds for use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-13 | — | — | EP | disclosed |
| US-4112207-A | Radiation-curable polymers bearing quaternary nitrogen groups | THE DOW CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4078071-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4049665-A | 1-OXO-2-PYRIDYL DISULFIDES; FOR USE IN SKIN CLEANSERS, SHAMPOOS, HAIR DRESSINGS, DISINFECTANTS, PRESERVATIVES | COLGATE-PALMOLIVE COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-4036975-A | FUNGICIDES, BACTERICIDES AND ANTIPROTOZOA AGENTS | XYNTEX (U.S.A) INC. (US) | 1977-07-19 | — | — | US | disclosed |
| US-3933947-A | INSECTICIDE, MITICIDE, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961231-B2 | NTCP inhibitors | HAVCR2, NPC1, HMGCR | IDO1 897/4885PNMT 2196/4885TAAR1 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.