Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16916475 | 0.91 | TDP1 (0.46) | KDM4ETDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL5175327 | 0.85 | TDP1 (0.54) | KDM4ETDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL3258895 | 0.85 | TDP1 (0.54) | KDM4ETDP1ALDH1A1LMNAHDAC3 | |
| SCHEMBL21480168 | 0.85 | KDM4E (0.46) | KDM4ETDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL12358653 | 0.83 | TDP1 (0.52) | KDM4ETDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL10392751 | 0.82 | ALOX5 (0.47) | KDM4ETDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL31301729 | 0.80 | HDAC3 (0.52) | KDM4ETDP1ALDH1A1LMNAHDAC3 | |
| SCHEMBL9332283 | 0.79 | ALOX5 (0.49) | KDM4ETDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL12450937 | 0.78 | HDAC1 (0.41) | TDP1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL25473056 | 0.77 | HDAC3 (0.55) | KDM4ETDP1ALDH1A1LMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458996-B | Fused pyrimidines as inhibitors of the p97 complex | 克里弗生物科学公司 | 2020-11-03 | — | — | CN | disclosed |
| US-4481360-A | 4H-1,2,4-Triazol-3-yl compounds | THE UPJOHN COMPANY (US) | 1984-11-06 | — | — | US | disclosed |